Overview

Abnormal plasma cells can crowd out or suppress the growth of other cells in the bone marrow that produce red blood cells, white blood cells, and platelets. They also reduce the creation of normal plasma cells, which lowers a person’s immunity.

Symptoms

Anemia, Fatigue, Bone pain, Hypercalcemia, weight loss, anemia, Fever.

Causes

The cancerous myeloma plasma cells proliferate and crowd out normal plasma cells . The proteins produced in large amounts can cause many of the symptoms of the disease by making the blood more thickened (viscous) and depositing the proteins in organs that can interfere with the functions of the kidneys, nerves, and immune system.

Diagnosis

Blood & urine Test, X-Ray, MRI, CT Scan, PET scan, Bone marrow aspiration and biopsy, Fat pad aspirate, Molecular testing of the tumor.

Prevention

With multiple myeloma, few cases are linked to risk factors that can be avoided.

Treatment

Induction therapy for rapid control of cancer and to help relieve symptoms, Consolidation with more chemotherapy or stem cell transplant,Maintenance therapy over a prolonged period to prevent cancer recurrence.Chemotherapy & Targeted Theray :Bortezomib, Thalidomide.

Everyday Life

People do not often experience multiple myeloma symptoms until they reach stage 3. At this stage, the cancer affects multiple areas of the body, causing complex symptoms.

Resources

https://www.medicinenet.com/multiple_myeloma/article.htm#multiple_myeloma_facts

https://www.cancer.net/cancer-types/multiple-myeloma/types-treatment