Overview

Nausea and vomiting are serious side effects of cancer therapy....

Symptoms

• Acute: Nausea and vomiting that happen within 24 hours after treatment starts.
• Delayed: Nausea and vomiting that happen more than 24 hours after chemotherapy. This is also called late nausea and vomiting.

Causes

• Radiation therapy may also cause nausea and vomiting.
• Other conditions may also increase the risk of nausea and vomiting in patients with advanced cancer.

Prevention

Acute and delayed nausea and vomiting with chemotherapy or radiation therapy are usually treated with drugs.

Treatment

Drugs Used to Prevent Nausea and Vomiting Caused by

• Chemotherapy: Dopamine receptor antagonists,Serotonin receptor antagonists,Corticosteroids , Substance P/NK-1
• antagonists:Aprepitant, Fosaprepitant

Everyday life

When CINV goes untreated, it affects upwards of 60% to 80% of patients with cancer. CINV not only negatively impacts the quality of life (QOL) of the patient, but also the QOL of the patient’s family. Without prevention and control of CINV, patients may experience many undesirable events that can affect their QOL and/or treatment outcomes, including discontinuation of chemotherapy, which highlights the need for adequate prevention and control measures.

Resources

https://www.cancer.gov/about-cancer/treatment/side-effects/nausea/nausea-pdq#_1
https://www.ajmc.com/journals/supplement/2017/managed-care-considerations-in-chemotherapy-induced-nausea-and-vomiting/overview-of-chemotherapy-induced-nausea-and-vomiting-and-evidence-based-therapies-article

Resources

https://www.cancer.gov/types/breast/patient/breast-treatment-pdq#_222

https://www.cancer.net/cancer-types/breast-cancer/types-treatment

https://www.mayoclinic.org/healthy-lifestyle/womens-health/in-depth/breast-cancer-prevention/art-20044676